College Ready is a targeted partnership consisting of two universities, 39 partner school districts, and more than 80 school campuses in Arkansas and Oklahoma. The Partnership is beginning its fourth year and has worked with more than 500 school teachers and administrators, and university faculty and administrators, in providing more than 42,000 hours of professional development to date. There are two primary components of College Ready: Master Teacher Workshops and Professional Learning Communities (PLCs). The focus of Master Teacher Workshops is enhancing teachers’ capacity to utilize inquiry-based instructional strategies in their specific content areas. PLCs are the mechanism for institutionalizing changes in instructional practices intended through Master Teacher Workshops, as well as sustaining the impact of College Ready beyond the formal life of the Partnership.